name: clawbio-pharmgx-reporter version: 0.1.0 description: Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) author: Manuel Corpas license: MIT tags:

• pharmacogenomics
• CPIC
• DTC-genetics
• precision-medicine inputs:
• name: input type: file format: [23andme, ancestrydna, tsv] description: Raw genetic data file from 23andMe or AncestryDNA outputs:
• name: report type: file format: markdown description: Pharmacogenomic report with gene profiles and drug recommendations metadata: openclaw: category: bioinformatics homepage: https://github.com/ClawBio/ClawBio min_python: "3.9" dependencies: []

🦖 PharmGx Reporter

Generate a pharmacogenomic report from consumer genetic data (23andMe, AncestryDNA).

What it does

1. Parses raw genetic data files (auto-detects 23andMe or AncestryDNA format)
2. Extracts 31 pharmacogenomic SNPs across 12 genes
3. Calls star alleles and determines metabolizer phenotypes
4. Looks up CPIC drug recommendations for 51 medications
5. Generates a markdown report with gene profiles, drug tables, and alerts

Genes covered

CYP2C19, CYP2D6, CYP2C9, VKORC1, SLCO1B1, DPYD, TPMT, UGT1A1, CYP3A5, CYP2B6, NUDT15, CYP1A2

Drug classes

Antiplatelet, opioids, statins, anticoagulants, PPIs, antidepressants (TCAs, SSRIs, SNRIs), antipsychotics, NSAIDs, oncology, immunosuppressants, antivirals

Usage

python pharmgx_reporter.py --input patient_data.txt --output report

Disclaimer

This tool is for research and educational purposes only. It is NOT a diagnostic device. Always consult a healthcare professional before making any medication decisions.